Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

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Effect of topical dorzolamide on rabbit central corneal thickness.

Our objective was to study the effect of dorzolamide on corneal hydration in an 18-week controlled experiment using ultrasonic pachymetry. Twenty-eight male rabbits were divided randomly into four groups. The 7 rabbits in each group received eye drops containing either 2% (w/v) dorzolamide or placebo in their right eye, or in their left eye. The 2% dorzolamide rabbits were treated every 8 h. Fe...

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BACKGROUND To determine the change in central corneal thickness over time and whether the use of long-term topical antiglaucoma medications influences central corneal thickness. DESIGN Case control study with retrospective and prospective data collection. PARTICIPANTS One hundred eighty-seven eyes of 187 glaucoma patients (mean follow up 6.92 ± 1.67 years) being treated with topical antigla...

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Endothelial function in patients with cornea guttata.

Measurements of corneal thickness, endothelial cell size, endothelial permeability to fluorescein, and intraocular pressure were made in two groups of human subjects: 21 persons with cornea guttata (early Fuchs dystrophy without epithelial edema) and 17 persons age- and sex-matched but with normal corneas. Statistically significant differences were found between the two groups in all four measu...

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Central Corneal Thickness in Children

Results: A total of 2079 children were included in the study, with ages ranging from birth to 17 years. Included were 807 whites, 494 Hispanics, and 474 African Americans, in addition to Asian, unknown race, and mixed-race individuals. African American children had thinner corneas on average than that of both white and Hispanic children (P .001 for both) by approximately 20 μm. Thicker median C...

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Central corneal thickness in Latinos.

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 2007

ISSN: 0003-9950

DOI: 10.1001/archopht.125.10.1345